Dementia Research Charity Chatathon

Epigenetics, Exploring Dark crevices of Genes and links to Alzheimer's

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Episode notes

On the 7th September 2020, Adam Smith hosted the Dementia Research Chatathon LIVE - to share information on the wide variety of research taking place across the world, and the raise money for Alzheimer's Research UK. Please continue to donate and help Adam meet his £5,000 target - details can be found at www.chatathon.uk.

In a way that everyone can understand, this video features Adam talking with:

Professor Katie Lunnon,  Professor of Dementia Genomics, University of Exeter. Katie works in the field of epigenetics and gene regulation. Her studies look in the brain to see if we can identify epigenetic differences in individuals with dementia as well as in the blood with the hope of identifying new biomarkers. Initially focusing on Alzheimer's disease but now expanding her studies to look at other dementias as well. Additionally Katie leads a number of functional studies, exploring proteins, iPSCs and gene editing in cell lines - @katielunnon

Dr Leonidas Chouliaras, Clinical Lecturer in Old Age Psychiatry, University of Cambridge. Leo is a clinician and epigeneticist, focused on Lewy Body Dementia. Working both on clinical cohorts, studying DNA methylation in blood samples as well as in autopsy brain tissues, isolating neurons with Lewy Bodies using laser-microdissection and comparing the epigenetic profiles with healthy looking neurons from the same donor or from controls - @chouliarasL