The Oxford AstraZeneca Vaccine is already being rolled out in the UK, and is the most ordered jab in the developing world. However, this weekend results from trials suggest the vaccine is ineffective against the South African strain of the virus. How big a blow is this news to the global fight against coronavirus? We ask Professor of Virology and Independent SAGE member Deenan Pillay. Plus: John Woodcock is given the job of investigating ‘extremism’ on left and right; How the Queen lobbied to hide her wealth; A rattled Keir Starmer seeks to seem “pro-business”; and the BBC’s Emma Barnett accused of Islamophobia. With Michael Walker and Ash Sarkar.