The Genetics Podcast
EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern
Episode notes
0:00 Introduction
2:00 The value of an English Literature degree in designing and analysing research studies in medicine
3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research
6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians, in genomics research
9:00 The scale of data available from linking electronic health data to research
11:15 The unclear bidirectional relationship between statins and cataracts
17:00 A potentially protective gene factor that can reduce the likelihood of cataracts in those who take statins
22:15 Striving for global, diverse representation in pharmacogenomics research
26:40 The risk of amyloid-related imaging abnormalities (ARIA) for a relatively new Alzheimer’s disease drug, and implications for future drug development
29:15 How pharmacogenomics fits into medicine and healthcare systems
31:30 The challenges of incorporating preventive care into existing healthcare systems
34:00 Building trust as a cornerstone of healthcare, community medicine, and research
39:00 Community views on pharmacogenomics
40:15 Closing remarks
Please consider rating and reviewing us on your chosen podcast listening platform!